EFMC-ASMC'19
Conferences > Upcoming events > EFMC-ASMC'19
Sunday September 1, 2019
09:00Excursions - Tour 1
14:00Excursions - Tour 2
15:30Registration
17:30Opening
Prof. Varinder K. AGGARWAL (UNIVERSITY OF BRISTOL, Bristol, United Kingdom)
Dr Spiros LIRAS (BIOGEN, Cambridge, United States)
Dr Yves P. AUBERSON (NOVARTIS & EFMC, Basel, Switzerland)
Dr Gene VAISBERG (CHEMBRIDGE CORPORATION, San Diego, United States)
Prof. Emmanuel MIKROS (UNIVERSITY OF ATHENS, Athens, Greece)
18:00Opening Lecture
The Art and Science of Total Synthesis and its Impact on Biology and Medicine: From the Fundamentals to the Translational (T01)
Prof. K.C. NICOLAOU
(RICE UNIVERSITY, Houston, United States)
19:00Welcome Reception
20:00End of the Day
Monday September 2, 2019
08:00Registration
Session Chair
Prof. Varinder K. AGGARWAL
(UNIVERSITY OF BRISTOL, Bristol, United Kingdom)
08:30Nature’s Medicine Chest: Opportunities for Synthesis and Drug Discovery (T02)
Prof. Margaret Anne BRIMBLE
(THE UNIVERSITY OF AUCKLAND, Auckland, New Zealand)
09:15Drug Discovery in Academia (T03)
Prof. Oliver PLETTENBURG
(LEIBNIZ UNIVERSITY HANNOVER, Hannover, Germany)
10:00Practical and Asymmetric Gilman-Speeter Synthesis of B-Lactams (OC01)
Prof. Plato MAGRIOTIS
(UNIVERSITY OF PATRAS, Patras, Greece)
10:15Coffee Break and Exhibition
10:45Discovery of First in Class, Orally Bioavailable p300/CBP HAT Domain Inhibitors (T04)
Dr Michael MICHAELIDES
(ABBVIE, North Chicago, United States)
11:30Novel Bacterial Topoisomerase Inhibitors (NBTI) with Potent Gram-Negative Activity (T05)
Dr Cornelia ZUMBRUNN
(IDORSIA PHARMACEUTICALS, Allschwil, Switzerland)
12:15Rapid Exploration of Synthetically Tractable Chemical Space and Lead Optimization Using a Combination of Reaction-Based Enumeration, Active Learning, and Free Energy Calculations (OC02)
Dr Tatjana BRAUN
(SCHRÖDINGER, Mannheim, Germany)
12:30Lunch and Exhibition
13:00Schrödinger Workshop: Using LiveDesign for Collaborative and Data Driven Drug Design
Session Chair
Dr Malin LEMURELL
(ASTRAZENECA, Gothenburg, Sweden)
14:00Catalytic Chirality Generation: New Strategies for Organic Synthesis (T06)
Prof. John BOWER
(UNIVERSITY OF BRISTOL, Bristol, United Kingdom)
14:45Nucleophilic Boron for the Synthesis of Functionalized Small Rings (T07)
Prof. Mariola TORTOSA
(AUTONOMOUS UNIVERSITY OF MADRID, Madrid, Spain)
15:30A Radical Approach for the Late-Stage Functionalization of Phosphinic Peptides (OC03)
Mr Angelos LELIS
(UNIVERSITY OF ATHENS, Athens, Greece)
15:45Coffee Break and Exhibition
16:15EFMC Prize Winner EFMC-YMCS 2018
Development of Release-And-Report Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Disorders (OC04)
Dr Cassandra LEE FLEMING
(UNIVERSITY OF GOTHENBURG, Gothenburg, Sweden)
16:30Photoinduced Assembly of C–N Bonds (T08)
Dr Daniele LEONORI
(UNIVERSITY OF MANCHESTER, Manchester, United Kingdom)
17:15Practical Heteroatom- and Group-Transfer Reactions (T09)
Dr Laszlo KURTI
(RICE UNIVERSITY, Houston, United States)
18:00Closing of the Day
Tuesday September 3, 2019
Session Chair
Prof. Emmanuel MIKROS
(UNIVERSITY OF ATHENS, Athens, Greece)
08:30Design and Synthesis of Chemical Probes for Bromodomains (T10)
Prof. Stuart CONWAY
(UNIVERSITY OF OXFORD, Oxford, United Kingdom)
09:15A Medicinal Chemist's Perspective on Solute Carriers: Avoiding or Targeting them (T11)
Dr Kim HUARD
(GENENTECH, San Francisco, United States)
10:00Stabilizing Inactive Conformations of MALT1 AS an Effective Strategy to Inhibit its Protease Activity (OC05)
Dr Jean-Baptiste LANGLOIS
(NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Basel, Switzerland)
10:15Coffee Break and Exhibition
10:45A Chemical Approach to Map Protein Interactions at the Cell Surface (T12)
Dr Erik HETT
(MERCK EXPLORATORY SCIENCE CENTER, Boston, United States)
11:30From Fragments to Antibody Drug Conjugates in Emerging Oncology Targeted Therapies (T13)
Dr Laurent SCHIO
(SANOFI, Vitry sur Seine, France)
12:15Macrocyclic Modalities for Modulation of Protein-Protein Interactions (OC06)
Dr Stephanie GUERET
(ASTRAZENECA MPI SATELLITE UNIT, Dortmund, Germany)
12:30Lunch and Exhibition
13:30Poster Session 1 (odd numbers)
Session Chair
Dr Gene VAISBERG
(CHEMBRIDGE CORPORATION, San Diego, United States)
14:30Awareness of PAINS (Pan Assay Interference Compounds) can Accelerate the Drug Discovery Process (T14)
Prof. Jonathan BAELL
(MONASH UNIVERSITY, Parkville, Australia)
15:15Artificial Intelligence in ADMET Modeling and Compound Profiling (T15)
Dr Karl-Heinz BARINGHAUS
(SANOFI, Frankfurt, Germany)
16:00Antimicrobial Activity of Curcumin Analog PGV-6, HGV-6 and GVT-6 (OC07)
Dr Leni RITMALENI
(GADJAH MADA UNIVERSITY, Yogyakarta, Indonesia)
16:15Coffee Break and Exhibition
16:45Sustainable by Design Anti-Trypanosomatid Small Molecules: an Aspirational Goal for Medicinal Chemistry (T16) - ChemMedChem Lecture
Prof. Maria Laura BOLOGNESI
(UNIVERSITY OF BOLOGNA, Bologna, Italy)
17:30Artificial Intelligence in de Novo Molecular Design (T17)
Dr Ola ENGKVIST
(ASTRAZENECA, Mölndal, Sweden)
18:15Closing of the Day
Wednesday September 4, 2019
Session Chair
Dr Yves P. AUBERSON
(NOVARTIS & EFMC, Basel, Switzerland)
08:30Amides and Chemical Education as Vehicles for Innovation (T18)
Prof. Neil GARG
(UNIVERSITY OF CALIFORNIA, Los Angeles, United States)
09:15Discovery of AZD5718, a Novel 5-lipoxygenase Activating Protein (FLAP) Inhibitor (T19)
Dr Malin LEMURELL
(ASTRAZENECA, Gothenburg, Sweden)
10:00Discovery of GSK701, a Novel Orally Effective Preclinical Drug Candidate for the Treatment of Malaria (OC08)
Dr Jose Ignacio MARTIN
(GSK, Tres Cantos, Spain)
10:15Coffee Break and Exhibition
10:45Design and Implementation of de Novo Biosynthetic Cascades (T20)
Prof. Sabine FLITSCH
(UNIVERSITY OF MANCHESTER, Manchester, United Kingdom)
11:30Catalysis for Total Synthesis (T21)
Prof. Alois FÜRSTNER
(MAX PLANCK INSTITUT FUR KOHLENFORSCHUNG, Muelheim an der Ruhr, Germany)
12:15Developing a ‘Reverse-Biomimetic’ Synthesis of Arogenate and its Analogues (OC09)
Ms Louise EAGLING
(UNIVERSITY OF BRISTOL, Bristol, United Kingdom)
12:30Lunch and Exhibition
13:30Poster Session 2 (even numbers)
Session Chair
Prof. Christoforos KOKOTOS
(UNIVERSITY OF ATHENS , Athens, Greece)
14:30Development and Application in Flow of Sustainable Synthetic Methodologies that Use Singlet Oxygen as Green Oxidant and Cascade Reaction Facilitator (T22)
Prof. Georgios VASSILIKOGIANNAKIS
(UNIVERSITY OF CRETE, Heraklion, Greece)
15:15Prize Ceremony
Dr Yves P. AUBERSON
(NOVARTIS & EFMC, Basel, Switzerland)
15:20EFMC Prize for a Young Medicinal Chemist in Academia
From the Elucidation of the Mechanism of Vitamin E to the Design of Innovative Drugs that Limit Inflammation and Enhance Resolution (OC10)
Dr Andreas KOEBERLE
(UNIVERSITY OF JENA, Jena, Germany)
15:35EFMC Prize for a Young Medicinal Chemist in Industry
Cipargamin-Biocatalysis in the Discovery and Development of an Antimalarial Drug (OC11)
Dr Radka SNAJDROVA
(NOVARTIS PHARMA AG, Basel, Switzerland)
15:50Coffee Break and Exhibition
16:20Flow Chemistry and Photochemistry as a Tool for Drug Discovery (T23)
Dr Jesus ALCAZAR
(JANSSEN RESEARCH & DEVELOPMENT, Toledo, Spain)
17:05Closing of the Day
20:00Symposium Banquet
Thursday September 5, 2019
Session Chair
Dr Spiros LIRAS
(BIOGEN, Cambridge, United States)
08:30Start Selective and Rigidify: The Discovery Path Towards the Next Generation of EGFR Tyrosine Kinase Inhibitors (T24)
Dr Harald ENGELHARDT
(BOEHRINGER-INGELHEIM, Vienna, Austria)
09:15RNA Therapeutics: New Chemical Modalities Becoming a Therapeutic Reality (T25)
Dr Konrad BLEICHER
(F.HOFFMANN-LA ROCHE LTD, Basel, Switzerland)
10:00Removable Directing Groups for Late-Stage Functionalisation (OC12)
Dr Miriam O'DUILL
(NATIONAL UNIVERSITY OF IRELAND, Galway, Ireland)
10:15Coffee Break and Exhibition
10:45TLR7/8 Antagonists: from Screening to in vivo Potency (T26)
Dr Claudia BETSCHART
(NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Basel, Switzerland)
11:30Allosteric Activation of a Master Metabolic Regulator AMPK: Drug Discovery Opportunities and Challenges (T27)
Dr Kimberly CAMERON
(PFIZER, Cambridge, United States)
12:15Closing Remarks & Prize Ceremony
12:30End of the Symposium

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