EFMC-YMCS 2017

4th EFMC Young Medicinal Chemist Symposium

 Vienna, Austria    August 31

Programme


14:15

Registration

15:00

Welcome and Opening

15:05

The Fascinating World of Medicinal Chemistry and Drug Discovery

Dr Christoph BOSS
IDORSIA PHARMACEUTICALS LTD, Allschwil, Switzerland

YMCS Competition Presentation Session I

15:35

OC01 - A Novel Hydantoin-Based Series of Dpre1 Inhibitors in M.Tuberculosis: Hit-to-Lead Optimization and Biological Profiling

Ms Olga BALABON
UNIVERSITY OF ANTWERP, Wilrijk, Belgium

15:55

OC02 - Target Elucidation of Novel Trypanosomatid Inhibitors
Winner of the young medicinal chemist meeting in the United Kingdom

Mr Andrew FRASER
UNIVERSITY OF ST ANDREWS, Ayr, United Kingdom

16:15

OC03 - Design, Synthesis and Biological Evaluation of New Artemisinin Hybrid Molecules
Winner of the young medicinal chemist meeting in Greece

Mr Antonios S. LETIS
UNIVERSITY OF PATRAS, Patras, Greece

16:35

OC04 - Development of Non-Covalent In Vivo Active Butyrylcholinesterase Inhibitors
Winner of the young medicinal chemist meeting in Slovenia

Mr Urban KOSAK
UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia

16:55

Flash Poster Presentations

FP01- 3rd-Generation Analogs of Meiogynine A, New Multiple Inhibitors of Anti-Apoptotic Proteins of Bcl-2 Family

Ms Alma ABOU SAMRA
INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES, Gif-sur-Yvette, France

FP02 - Slow But Steady Wins The Race: Influenza A M2/V27a Resistance Mechanism

Dr Marta BARNIOL-XICOTA
UNIVERSITAT DE BARCELONA, Leuven, Belgium

FP03 - New Vistas in Lithium Halocarbenoids Mediated Homologations

Mrs Laura CASTOLDI
UNIVERSITY OF VIENNA, Vienna, Austria

FP04 - Synthesis of Hydroxy Lactones by Selenium-Mediated Oxidation/Cyclization of Alkenoic Acids Under Eco-Flow Conditions

Dr Bruno CERRA
UNIVERSITY OF PERUGIA, Perugia, Italy

FP05 - Metabolite Identification and Total Synthesis of Metabolically Stabilized Analogs of The Natural Product Pironetin

Ms Sara COULUP
UNIVERSITY OF MINNESOTA, Minneapolis, United States

FP06 - New Allosteric Modulator of The Cb2 Receptor and its Potential Application in Neuropathic Pain

Dr Francesca GADO
UNIVERSITŔ DI PISA, Pisa, Italy

FP08 - Small Molecules for In Situ Cell Manipulation as A Regenerative Medicine Strategy

Dr Laia JOSA CULLERE
UNIVERSITY OF OXFORD, Oxford, United Kingdom

FP09 - Synthesis and Biological Activity of Novel Atypical Dopamine Re-Uptake Inhibitors for The Treatment of Dementia

Mr Predrag KALABA
UNIVERSITY OF VIENNA, Vienna, Austria

FP10 - A Multifaceted α-Enaminone: Adaptable Building Block for Synthesis of Heterocyclic Scaffolds Through Conceptually Distinct 1,2-, 1,3-, 1,4- and C-O Bond Forming Annulations

Mr David LANKRI
HEBREW UNIVERSITY, Jerusalem, Israel

FP11 - Investigating The Impact of Covalency on Protac-Mediated Degradation of Btk

Ms Hannah LITHGOW
UNIVERSITY OF STRATHCLYDE & GSK, Glasgow, United Kingdom

FP12 - Protein Modelling and Virtual Screening to Identify New Inhibitors Targeting The Lsrk Kinase

Ms Prasanthi MEDARAMETLA
UNIVERSITY OF EASTERN FINLAND, Kuopio, Finland

FP13 - Towards A Pharmacological Neuroregenerative Therapy

Dr Laura MOLA
UNIVERSITY OF OXFORD , Oxford, United Kingdom

FP14 - Novel α-Amino Diarylphosphonates as Inhibitors of E.Coli Clpp Protease

Mr Carlos MORENO-CINOS
UANTWERPEN, Wilrijk, Belgium

FP15 - Design of Novel Imidazopyridazines as Strong Haspin Inhibitors

Mr Matthieu PLACE
ICOA CNRS UMR 7311, ORLEANS, France

FP16 - Design of New Ezh2 Inhibitors Using Pharmacophoric Models

Ms Filipa RAMILO-GOMES
INSTITUTO SUPERIOR TÉCNICO -UNIVERSIDADE DE LISBOA, Lisbon, Portugal

FP17 - Development of Novel Prodrug Designs Activated by Nitroreductase

Mr Andrew TANG
MONASH UNIVERSITY, Melbourne, Australia

FP18 - Synthesis of Heterocycle-Bridged Peptidic Macrocycles Via 1,3-Diyne Transformations

Mr Steven VERLINDEN
VRIJE UNIVERSITEIT BRUSSEL, Elsene, Belgium

FP19 - Controlling The Redox Transcription Factor Regulator Pirin: Rational Design, Activity Cliffs and Metal-Dependency

Dr Birgit WILDING
THE INSTITUTE OF CANCER RESEARCH, London, United Kingdom

FP20 - Indolactam V and Derivatives: Potential Tools for Contact-Independant iPSC Culture

Dr Laurence SILPA
UNIVERSITY OF OXFORD, Oxford, United Kingdom

17:35

YMCS Poster presentation session 1 & Networking drink

19:00

End of the day

YMCS Competition Presentation Session II

08:30

OC05 - Identification of potent inhibitors of the anti-infective target DXS using ligand-based virtual screening
Winner of the young medicinal chemist meeting in Germany (DPhG)

Prof. Anna K. H. HIRSCH
HELMHOLTZ INSTITUTE FOR PHARMACEUTICAL RESEARCH SAARLAND, Saarbrücken, Germany

08:50

OC06 - In Situ Ugi Four-Component Reaction for the Protein-Templated Identification of Inhibitors of Endothiapepsin
Winner of the young medicinal chemist meeting in the Netherlands

Mr M. Yagiz ÜNVER
UNIVERSITY OF GRONINGEN, Groningen, The Netherlands

09:10

OC07 - Design and Synthesis of Functionalized Monocyclic 3-Amino-1-Carboxymethyl-Beta-Lactams as Potential Inhibitors of Penicillin Binding Proteins of Resistant Bacteria

Ms Lena DECUYPER
GHENT UNIVERSITY, Gent, Belgium

09:30

OC08 - Discovery and Optimization of Novel Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anticancer Agents
Winner of the young medicinal chemist meeting in Italy

Dr Sergio VALENTE
SAPIENZA UNIVERSITY OF ROME, Rome, Italy

09:50

OC09 - Bicyclic Constrained Peptides Targeting the EGF-EGFR Interaction
Winner of the young medicinal chemist meeting in Spain

Mr Salvador GUARDIOLA
INSTITUTE FOR RESEARCH IN BIOMEDICINE, Barcelona, Spain

10:10

Coffee Break

YMCS Competition Presentation Session III

10:30

OC10 - Discovery and Characterization of Novel Potent F508-Del Cftr Correctors

Dr Federico SORANA
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, GENOVA, Italy

10:50

OC11 - Facing Non-Alcoholic Steatohepatitis with Multitarget Compounds

Dr Daniel MERK
ETH ZÜRICH, Zürich, Switzerland

11:10

OC12 - Development of Ligands for the Short-Chain Fatty Acid Receptor Ffa2
Winner of the young medicinal chemist meeting in Denmark

Mr Anders HOJGAARD HANSEN
UNIVERSITY OF SOUTHERN DENMARK, Odense M, Denmark

11:30

OC13 - Fluorophore One-Atom-Controlled Recognition of DNA/RNA Secondary Structure
Winner of the young medicinal chemist meeting in Croatia

Dr Tamara SMIDLEHNER
RUDER BOSKOVIC INSTITUTE, Zagreb, Croatia

11:50

Lunch & Poster session 2

YMCS Competition Presentation Session IV

13:15

OC14 - Building-up Molecular Complexity with Carbenoids: New Vistas in Homologation Chemistry
Winner of the young medicinal chemist meeting in Austria

Dr Vittorio PACE
UNIVERSITY OF VIENNA, Vienna, Austria

13:35

OC15 - The Role of The Sulfonyl Group on The Conformational Preferences Of Bis-Aromatic Compounds ¬ 5-Ht6 Receptor Antagonists and Beyond
Winner of the young medicinal chemist meeting in Poland

Dr Jakub STARON
INSTITUTE OF PHARMACOLOGY PAS, Krakow, Poland

13:55

OC16 - The Catalytic Mechanism of The Iron-dependent Sulfoxide Synthase EgtB
Winner of the young medicinal chemist meeting in Switzerland

Dr Kristina GONCHARENKO
UNIVERSITY OF BASEL, Basel, Switzerland

14:15

OC17 - Modular Assembly of Reversible Multivalent Targeting Drug Conjugates
Winner of the young medicinal chemist meeting in Portugal

Mr Fábio Miguel FIGUEIREDO SANTOS
RESEARCH INSTITUTE FOR MEDICINES (IMED.ULISBOA), Lisboa, Portugal

14:35

OC18 - Molecular Recognition and Activation Mechanisms of Bitter Taste Receptors
Winner of the young medicinal chemist meeting in Israel

Dr Antonella DI PIZIO
THE HEBREW UNIVERSITY OF JERUSALEM, Rehovot, Israel

14:55

Voting break

15:10

Challenging Medicinal Chemistry!

Dr Peter NUSSBAUMER
LEAD DISCOVERY CENTER, Dortmund, Germany

15:40

Closing and award ceremony

16:00

End of the Symposium