EFMC-ASMC'19

EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry

 Athens, Greece    September 1-5, 2019

Opening Lecture

Opening Lecture
The Art and Science of Total Synthesis and Its Impact on Biology and Medicine: From the Fundamentals to the Translational (T01)

Prof. K.C. NICOLAOU
Prof. K.C. NICOLAOU
RICE UNIVERSITY, Houston, United States
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Invited Speakers

Flow Chemistry and photochemistry as a Tool for Drug Discovery (T23)

Dr Jesus ALCAZAR
Dr Jesus ALCAZAR
J&J PHARMACEUTICAL RESEARCH AND DEVELOPMENT, Toledo, Spain
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Awareness of PAINS (Pan Assay Interference Compounds) can Accelerate the Drug Discovery Process (T14)

Prof. Jonathan BAELL
Prof. Jonathan BAELL
MONASH UNIVERSITY, Parkville, Australia
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Artificial Intelligence in ADMET Modeling and Compound Profiling (T15)

Dr Karl-Heinz BARINGHAUS
Dr Karl-Heinz BARINGHAUS
SANOFI, Frankfurt, Germany
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TLR7/8 Antagonists: from Screening to in vivo Potency (T26)

Dr Claudia BETSCHART
Dr Claudia BETSCHART
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Basel, Switzerland
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RNA Therapeutics: New Chemical Modalities Becoming a Therapeutic Reality (T25)

Dr Konrad BLEICHER
Dr Konrad BLEICHER
F.HOFFMANN-LA ROCHE LTD, Basel, Switzerland
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Sustainable by Design Anti-Trypanosomatid Small Molecules: an Aspirational Goal for Medicinal Chemistry (T16)

Prof. Maria Laura BOLOGNESI
Prof. Maria Laura BOLOGNESI
UNIVERSITY OF BOLOGNA, Bologna, Italy
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Catalytic Chirality Generation: New Strategies for Organic Synthesis (T06)

Prof. John BOWER
Prof. John BOWER
UNIVERSITY OF BRISTOL, Bristol, United Kingdom
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Nature’s Medicine Chest: Opportunities for Synthesis and Drug Discovery (T02)

Prof. Margaret Anne BRIMBLE
Prof. Margaret Anne BRIMBLE
THE UNIVERSITY OF AUCKLAND, Auckland, New Zealand
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Allosteric Activation of a Master Metabolic Regulator AMPK: Drug Discovery Opportunities and Challenges (T27)

Dr Kimberly CAMERON
Dr Kimberly CAMERON
PFIZER, Cambridge, United States
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Design and Synthesis of Chemical Probes for Bromodomains (T10)

Prof. Stuart CONWAY
Prof. Stuart CONWAY
UNIVERSITY OF OXFORD, Oxford, United Kingdom
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You Get What You Start With - Next Generation EGFR TKIs (T24)

Dr Harald ENGELHARDT
Dr Harald ENGELHARDT
BOEHRINGER-INGELHEIM, Vienna, Austria
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Artificial Intelligence in de Novo Molecular Design (T17)

Dr Ola ENGKVIST
Dr Ola ENGKVIST
ASTRAZENECA, Mölndal, Sweden
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Design and Implementation of de Novo Biosynthetic Cascades (T20)

Prof. Sabine FLITSCH
Prof. Sabine FLITSCH
UNIVERSITY OF MANCHESTER, Manchester, United Kingdom
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Catalysis for Total Synthesis (T21)

Prof. Alois FÜRSTNER
Prof. Alois FÜRSTNER
MAX PLANCK INSTITUT FUR KOHLENFORSCHUNG, Muelheim an der Ruhr, Germany
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Amides and Chemical Education as Vehicles for Innovation (T18)

Prof. Neil GARG
Prof. Neil GARG
UNIVERSITY OF CALIFORNIA, Los Angeles, United States
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A Chemical Approach to Map Protein Interactions at the Cell Surface (T12)

Dr Erik HETT
Dr Erik HETT
MERCK EXPLORATORY SCIENCE CENTER, Boston, United States
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Title to be announced (T11)

Dr Kim HUARD
Dr Kim HUARD
GENENTECH, San Francisco, United States
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Practical Heteroatom- and Group-Transfer Reactions (T09)

Dr Laszlo KURTI
Dr Laszlo KURTI
RICE UNIVERSITY, Houston, United States
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Discovery of AZD5718, a Novel 5-lipoxygenase Activating Protein (FLAP) Inhibitor (T19)

Dr Malin LEMURELL
Dr Malin LEMURELL
ASTRAZENECA, Mölndal, Sweden
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Photoinduced Assembly of C–N Bonds (T08)

Dr Daniele LEONORI
Dr Daniele LEONORI
UNIVERSITY OF MANCHESTER, Manchester, United Kingdom
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Discovery of First in Class, Orally Bioavailable p300/CBP HAT Domain Inhibitors (T04)

Dr Michael MICHAELIDES
Dr Michael MICHAELIDES
ABBVIE, North Chicago, United States
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Drug Discovery in Academia (T03)

Prof. Oliver PLETTENBURG
Prof. Oliver PLETTENBURG
LEIBNIZ UNIVERSITY HANNOVER, Hannover, Germany
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From Fragments to Antibody Drug Conjugates in Emerging Oncology Targeted Therapies (T13)

Dr Laurent SCHIO
Dr Laurent SCHIO
SANOFI, Vitry sur Seine, France
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Synthesis of Versatile Intermediates Through Copper Catalysis (T07)

Prof. Mariola TORTOSA
Prof. Mariola TORTOSA
AUTONOMOUS UNIVERSITY OF MADRID, Madrid, Spain
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Development and Application in Flow of Sustainable Synthetic Methodologies that Use Singlet Oxygen as Green Oxidant and Cascade Reaction Facilitator (T22)

Prof. Georgios VASSILIKOGIANNAKIS
Prof. Georgios VASSILIKOGIANNAKIS
UNIVERSITY OF CRETE, Heraklion, Greece
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Novel Bacterial Topoisomerase Inhibitors (NBTI) with Potent Gram-Negative Activity (T05)

Dr Cornelia ZUMBRUNN
Dr Cornelia ZUMBRUNN
IDORSIA PHARMACEUTICALS, Allschwil, Switzerland
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Oral Communications

Rapid Exploration of Synthetically Tractable Chemical Space and Lead Optimization Using a Combination of Reaction-Based Enumeration, Active Learning, and Free Energy Calculations (OC02)

Dr Tatjana BRAUN
Dr Tatjana BRAUN
SCHRÖDINGER, Mannheim, Germany
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Developing a ‘Reverse-Biomimetic’ Synthesis of Arogenate and its Analogues (OC08)

Ms Louise EAGLING
Ms Louise EAGLING
UNIVERSITY OF BRISTOL, Bristol, United Kingdom
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Stabilizing Inactive Conformations of MALT1 AS an Effective Strategy to Inhibit its Protease Activity (OC04)

Dr Jean-Baptiste LANGLOIS
Dr Jean-Baptiste LANGLOIS
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, Basel, Switzerland
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A Radical Approach for the Late-Stage Functionalization of Phosphinic Peptides (OC03)

Mr Angelos LELIS
Mr Angelos LELIS
UNIVERSITY OF ATHENS, Athens, Greece

Practical and Asymmetric Gilman-Speeter Synthesis of B-Lactams (OC01)

Prof. Plato MAGRIOTIS
Prof. Plato MAGRIOTIS
UNIVERSITY OF PATRAS, Patras, Greece
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Discovery of GSK701, a Novel Orally Effective Preclinical Drug Candidate for the Treatment of Malaria (OC07)

Dr Jose Ignacio MARTIN
Dr Jose Ignacio MARTIN
GSK, Tres Cantos, Spain
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Removable Directing Groups for Late-Stage Functionalisation (OC09)

Dr Miriam O'DUILL
Dr Miriam O'DUILL
NATIONAL UNIVERSITY OF IRELAND, Galway, Ireland
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Antimicrobial Activity of Curcumin Analog PGV-6, HGV-6 and GVT-6 (OC06)

Dr LENI RITMALENI
Dr LENI RITMALENI
GADJAH MADA UNIVERSITY, Yogyakarta, Indonesia
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